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Cystic fibrosis (CF) is a genetic disease affecting approximately 30,000
children and adults in the United States. A defective gene causes the
body to produce an abnormally thick, sticky mucus that clogs the lungs
and leads to life-threatening lung infections. These thick secretions
also obstruct the pancreas, preventing digestive enzymes from
reaching the intestines to help break down and absorb food. More than
10 million Americans are unknowing, symptomless carriers of the
defective CF gene. An individual must inherit two defective CF genes
¾ one from each parent ¾ to have CF. Each time two carriers
conceive, there is a 25 percent chance that their child will have CF; a
50 percent chance that the child will be a carrier of the CF gene; and a
25 percent chance that the child will be a non-carrier. CF occurs in
approximately one of every 3,200 live Caucasian births (in one of every
3,900 live births of all Americans). About 1,000 new cases of CF are
diagnosed each year. More than 80 percent of patients are diagnosed
by age three; however, nearly 10 percent of newly diagnosed cases
are age 18 or older.
children and adults in the United States. A defective gene causes the
body to produce an abnormally thick, sticky mucus that clogs the lungs
and leads to life-threatening lung infections. These thick secretions
also obstruct the pancreas, preventing digestive enzymes from
reaching the intestines to help break down and absorb food. More than
10 million Americans are unknowing, symptomless carriers of the
defective CF gene. An individual must inherit two defective CF genes
¾ one from each parent ¾ to have CF. Each time two carriers
conceive, there is a 25 percent chance that their child will have CF; a
50 percent chance that the child will be a carrier of the CF gene; and a
25 percent chance that the child will be a non-carrier. CF occurs in
approximately one of every 3,200 live Caucasian births (in one of every
3,900 live births of all Americans). About 1,000 new cases of CF are
diagnosed each year. More than 80 percent of patients are diagnosed
by age three; however, nearly 10 percent of newly diagnosed cases
are age 18 or older.
Established in 1955, the mission of the Cystic Fibrosis
Foundation is to assure the development of the means to cure
and control cystic fibrosis (CF) and to improve the quality of life
for those with the disease.
Foundation is to assure the development of the means to cure
and control cystic fibrosis (CF) and to improve the quality of life
for those with the disease.
